As expected, Seahawks safety Kam Chancellor will miss a second straight game, the result of a groin injury that also kept him out of last week's win over the Atlanta Falcons. Chancellor did not practice during the week and was listed as doubtful on Friday's injury report, and he indeed will be inactive for Sunday night's game at Arizona.

Kelcie McCray is expected to start a second straight game in Chancellor's place, and Seahawks coach Pete Carroll expressed optimism Friday that Chancellor will be back for next week's game at New Orleans.

"We certainly think that," Carroll said. "We thought he would have a shot this week, he just couldn't get there. Next week is quite likely, hopefully we'll get it done."

Also out because of injuries against the Cardinals are linebacker Kevin Pierre-Louis (ankle), who started last week at the strongside spot with Mike Morgan on injured reserve, running back Thomas Rawls (fibula), tight end Luke Willson (knee) and defensive tackle Quinton Jefferson (knee).

Rookie running back C.J. Prosise is active, meaning he'll see his first game action since sustaining a wrist injury in the season opener. With C.J. Spiller inactive for Sunday's game, that would seem to indicate that Prosise will have a significant role against the Cardinals as Seattle's third-down back. That was the role the Seahawks envisioned for Prosise when they drafted him, and one Spiller has filled in his two games with Seattle.

For Arizona, quarterback Carson Palmer is active after being listed as questionable with a hamstring injury. The Cardinals will be without John Brown, one of their top receivers, after it was discovered this week that a sickle-cell trait is behind what was believed to be a hamstring injury.

Here are the inactives for both team:

Seattle Seahawks

RB C.J. Spiller

S Kam Chancellor

RB Thomas Rawls

LB Kevin Pierre-Louis

G Rees Odhiambo

TE Luke Willson

DT Quinton Jefferson.

Arizona Cardinals

WR John Brown

CB Brandon Williams

LB Gabe Martin

G Cole Toner

DT Olsen Pierre

DT Ed Stinson

DT Xavier Williams