Featuring postgame quotes from the following:

Head Coach Mike Macdonald

MIKE MACDONALD: That's a result of good football team that outplayed us in three phases, and then it gets out of hand when you're doing the things we did today where we didn't help ourselves as well. It's a laundry list of things. We can go line item by line item if you want. The long and short of it is we got outplayed, outcoached, and we got to go make it right. Feel like it's too often we have had this conversation with you guys of going back to work on Tuesday and hitting this thing head on and seeing if we can get this thing turned around against a good Rams team coming in here.

How different does that game feel if you capitalize in the red zone on those two second quarter trips?

MIKE MACDONALD: Hard to tell if it flips, but you feel like you're right in it. Again, it's a story of red zone, us not getting stops in the red zone that we need, and then not being able to run the ball inside the five-yard line. We need to be better there for sure.

The one I guess where Geno fell back, what happened on that?

MIKE MACDONALD: I think he just got stepped on. You guys might have seen it. I didn't see it. He either got tripped or got stepped on.

Just big picture looking at the miscues made today, how do you feel the guys were trying to handle that in the moment. Seemed like obviously Derick Hall and Jarran Reed got into it...

MIKE MACDONALD: Well there is some frustration there. Look, our guys are connected, and they have each other's backs. They are emotional. There are going to be flare-ups and stuff. Seems like it calmed down. Wasn't a smart penalty. Just that's not how we train our guys to attack quarterbacks, so wasn't a smart move.

Where is your concern level with where the run game is at now? Second time in three, four games you've gone out there with under 2.2 yards per carry.

MIKE MACDONALD: Yeah, I would say it's a major concern. We've got to make it right. If I knew the one answer, I would give that to you right now. Seems like it's a litany of things. We've got to go to work on it. Right now, we can't control the tempo of games. We've got to go to work.

Any update on Dre'Mont Jones?

MIKE MACDONALD: We'll see. I think he finished the game, so we'll take it from there.

Was DK Metcalf close to playing at all?

MIKE MACDONALD: I mean, he's only missed, what, two games in his career? I think that speaks for itself on his work ethic. I know he was trying to do everything humanly possible to play. It became clear later in the week he wasn't going to be able to go.

How much of an impact do you think not having him had on the offense?

MIKE MACDONALD: No, DK Metcalf is one of one, but we've got a lot of really good players that can play. We expect them to go in and execute at a high level. We need to be able to move the ball on the ground and in the air. We've got to be able to score in the red zone. DK wouldn't have been out there on the goal line on the one- or two-yard line.

What did you make of Ernest Jones IV's first game with you guys?

MIKE MACDONALD: Tough to tell right now. Felt like he made some plays out in space. Got to look at the run game on some of those runs that were getting out and figure out what's going on there.

Some of these games, just how tough is the situations Geno has been in, whether it's the score or the run game?

MIKE MACDONALD: It's too often we're in throw-mode at the end. Again, it starts with dictating terms to the other team, controlling the game, the pace of the game, taking care of the football. So yeah, we've put him in tough situations late in game for sure.

Picking off Josh Allen for the first time in like 300 pass attempts for him, what did that mean I guess just as far as that moment?

MIKE MACDONALD: It was a lone kind of bright spot in the game. Felt like we had a chance to really turn the momentum there and Josh had a great technique on that play, and then when he had the opportunity, he took advantage of it. So that was great at the time. Felt like we had a chance to get the thing rolling.

How indicative is or is this not of where you are in this program right now?

MIKE MACDONALD: I think that's a good question. We talk about stacking wins around here, and when you're going on and off, back and forth, it's frustrating. You want to be able to build on the good things that we're doing so we can get our program to where we want it to go. When you take steps back like today, it's very sobering, frustrating. But this is the NFL. If you don't bring it and have your best against good teams, you're not going to win those games. Our guys know that. As coaches we've got to prepare our guys the best we can. We've got to call great games. This whole thing has to keep coming together. Time is ticking as we say. We are about halfway through the season now. But you take a step back, I mean, right in the thick of it in the division, and this game coming up is going to be a big one.

Seemed to really emphasize heavy personnel packages today. Extra offensive lineman and stuff. Was that something you guys were geared up for and what was giving you guys issues?

MIKE MACDONALD: Well it was more than they've shown on tape in those situations, but you still have to be ready for it. I thought we had a solid plan. Probably could have had some more front flexibility on that front to have some more answers, maybe some more movements. Those are things we talked about. You're trying to adjust throughout seeing where the ball is hitting to see if we can get some anchor points or play blocks better. So (a) combination of not trying to scrap what you have but also maybe just calm it down.

It wasn't good enough when they went to their big 12 personnel.

As up and down as it's been, do you even have a good read on whether your best would be as good as Buffalo or not know that yet?

MIKE MACDONALD: No, I think everybody on this field knows our best can compete with them. And look, Buffalo is a great team. Been doing this thing for a long time. The record speaks for themselves. They've got great players. That's a vote of confidence in our guys, our people.

QB Geno Smith

Just how frustrating in general is this day, kind of all the mistakes you guys made, the red zone drives in particular?

GENO SMITH: Yeah, extremely frustrating. I thought we prepared really well this week. I thought the guys were dialed in, we had great energy. Obviously, it didn't show up on game day today. We had too many self-inflicted wounds. That's been our story this season. We got down there in the red zone twice, had a shot at points, and came away with nothing. Well, we got three points, but we want to score touchdowns. Those are things that, again, we've got to be better at. I'm going to look at myself first and see what I've got to do better and take it from there.

How much different does a game feel if you're able to punch a ball in in those situations and tie it up or take a lead early?

GENO SMITH: I think it's a much different game. Hats off to Buffalo. They came in and beat us at home. Their fans travel well. It was really loud in there and kind of felt like we were on the road at times. They came out and fought and beat us. We can say we made mistakes, but they capitalized. Those are things we've got to get better at, and we got a big week ahead so the time is now.

What did happen I guess on the one where you fell down on the fourth down?

GENO SMITH: I thought that was pretty obvious. You could see it.

You guys have had to play from behind a number of times in recent weeks. How challenging has it been to do it as often as you needed to it here over the last stretch?

GENO SMITH: You never want to play from behind, but those are the cards we were dealt and you've got to do it. We put ourselves in those positions, so if there is anyone to be frustrated at it's our own self. We can play from behind. We have shown that we can fight back and get back into games. You don't want to make a living out of that. For us, we start talking about fast. Two three-and-outs to start the game is unacceptable. That is not the standard. Just the way in which started the second half, didn't get points; had a turnover; not the standard. And so when you talk about all the things we want to do well, I don't think we did any of those today. We've got to look at ourselves, in the mirror, and take it from there.

What do you need to do the next few days to get this behind you and move on?

GENO SMITH: First of all, got to own it and learn from it. Each one of those games, whether you won or lose, it's a lesson to be learned. That's the major thing, is we learn the lessons. Never want to go from a game and say we just put it behind us. That's the wrong way to look at it. Got to learn from your mistakes and own it. Those are things I'm going to do personally and I know our team is going to do as well. We're going to take it from there. One day at a time.

FS Coby Bryant

(On the challenges presented by Buffalo's offense) "Obviously, they run the ball. That's something we have to continuously work on. It's just about execution at the end of the day."

(On the frustration of this game after last week's game) "Extremely frustrating. Obviously, we wanted to come in and keep it rolling. But like I said, it's about the little things right now that we need to get done and get right and get fixed so we can continue to win and keep going."

(On how far he thinks Seattle is from a team like Buffalo, and the other top teams in the league) "Not far at all. It's us right now. We're beating ourselves. It's about us. Once we come together and play our style of football, we'll be good."

(On the mood at halftime) "We were good. The game wasn't over, we were going to fight to the end. That's who we are. Things are going to happen in a football, that's part of this sport. We just got to keep going and keep pushing."

(On seeing CB Josh Jobe get his first interception, was that a positive note) "100 percent. He had a great week of practice. He made a ton of plays. We expected that from him. He stepped up, played big. I'm extremely happy for him."

DT Byron Murphy II

(On what went wrong) "We couldn't stop the run when we needed to. That really was the biggest thing. We just couldn't stop it and got outplayed. We just have to get better."

(On Mike Macdonald's message after the game) "We just have to get back to work. We just have to get back to work and keep going. We can't beat ourselves up and be down on ourselves about the loss. We have to pick our heads up and keep moving."

(On why the Bills were able to keep Josh Allen clean today) "They were just playing good football. They weren't doing anything special really. They just played great football. Good team and they came out here and wanted it more and they got the [win]."

(On if the Bills did anything different than what they saw on film) "No. They did everything that we've seen on film. We just came up short."

LB Ernest Jones IV

(On playing the Bills in back-to-back games) "It doesn't happen too often. It was kind of a similar game. Didn't win both times I played them. It was kind of different playing the same team twice. Coming in here, we expected to win, but we just fell short."

(On if they had an idea of what they were going to do coming into the game) "They're really not going to do too much. The Bills want to do their best and execute at that level. They didn't come in here and do anything special. Of course, they have special runs and passes for this team, but they come out and they execute what they do at a high level."

(On getting up to speed with a short week and adjusting to the team) "I will say this, the plays in a sense are mirrored and the same from Tennessee. It's just different terminology. You're trying to get on the same page with the guys in front of you and behind you. That was kind of different. For me, just come in here, go out there and tackle and do what I can to help."

LB Derick Hall

(On if he felt the defense had a sloppy performance) "I don't know. I can't assess that right now. I know we had a lot of missed tackles, and that's just something we've been working on throughout the season. So, like I said, it's just an overall practical performance, and it stings, it hurts, but we have to be ready to go. L.A.'s on a good run, and they're coming here next week."

(On the conversation with Jarran Reed) "To just be smart. He loves the game. I love the game, and in that moment, things got heated. But he's a leader. He's the leader of our group, and when stuff hits the fan, you have to lean on the guys. And maybe we both could have done something a little bit better, but he wants me to go out and play smart, play fast, play physical, and that was basically his message in that moment."

C Connor Williams

(On what happened during the fourth downplay) "I'm not sure. I'm going to have to go back and look at the film and see what happened, but at the end of the day, I mean fourth and one, you can't allow penetration; you got to set the tone as the line, and so that's on us."

(On if he feels like this team is lacking discipline) "I think at the end of the day, we got the right attitude. We got the right men in the room, and it's just about focusing on the details and being able to build on them one day at a time, one step at a time."

(On Mike Macdonald's message to the team after the game) "We see the wall. We know the wall in front of us, and it's about going through the wall."

CB Riq Woolen

(On how it felt to get back on the field) "It felt good, honestly. I just wish we could've won, that's really what it is for me. It doesn't make any difference if I'm on the field or not, we're just not winning. It felt good to be back, but I just wanna win. We know we can get it right."

(On it feeling disjointed out there defensively and what he can point to in that regard) "Honestly, I don't know, we've got to go watch the film. Other than that, we still finished the game and we still fought. We just lost to a better team today, and we just got to be better next time."

(On if it felt like today was as sloppy as it seemed) "You never know until you look at the film. I don't know how you all view it. We lost today because they were better, and that's it. Other than that, we're going to watch film and do what we do. But other than that, game over, and now we've got to (focus on) the next one."

DT Roy Robertson-Harris

(On whether the defensive line had a communication gap or the Bills' style caused confusion) "They're a good football team, everybody knows that. They get paid too. One of the best teams in AFC. We've just got to execute, do what we do. They're going to make plays and they're going to do what they do, but it's all about what we do upfront. As a unit, we just got to make sure we're all on the same page."

(On it being his second week with the Seahawks and if he could tell a difference in his comfort level) "Everything's getting better each day. Still learning the scheme, but I've got a lot of good guys around me that are looking out for me and making sure I'm where I'm supposed to be and the communication, all that stuff is where it's supposed to be. So, everything's going up. Doing good right now."

(On the best way to correct penalties) "Just getting back to playing how we know how to play. Playing clean. We'll go back and watch it, see what needs to be corrected, and then we'll get back to playing ball like we know how."