PHOTOS: 5 Things To Know About The Seahawks' Week 6 Matchup Against The 49ers

Geno Smith's 1,446 yards leads the league this season. Smith also leads the league in completions (143) and attempts (199).

This will be the 51st regular season meeting between the two clubs with Seattle leading the series, 29-21.

The Seahawks hold a 24-7 prime-time home record since 2010 and play their first of two Thursday night games this season. Seattle is 10-5 on Thursday Night Football since the 2010 season.

Tyrel Dodson needs 1.0 sack to set his single-season career-high with 3.0.

The Seahawks' 79-37 is the 5th-best home record in the NFL since 2010.