The Seattle Seahawks (3-2) take on the San Francisco 49ers (2-3) for Week 6 at Lumen Field. Take a look at what local and national media are predicting for Sunday's game. Click here to learn how to watch, listen, and stream the action.

Bob Condotta, Seattle Times: Seahawks 24, 49ers 21

"As banged up as are the Seahawks, the 49ers aren't at full strength without Christian McCaffrey. While the 49ers have looked like their old selves in blowouts of the Jets and Patriots, they've been mortal in their other three. Going on the road on a short week and coming off a stunning home loss to Arizona provides the Seahawks their best chance in three years to beat the 49ers."

Matt Calkins, Seattle Times: 49ers 24, Seahawks 21

"Seattle has been dominated on the line of scrimmage, and the 49ers are one of the more physical teams they've faced all year. Look for San Francisco to hand Seattle its third straight loss as September euphoria morphs into October panic."

Mike Vorel, Seattle Times: 49ers 30, Seahawks 20

"Even without Christian McCaffrey, the 49ers remain dedicated to the run, as Jordan Mason sits second in the NFL in rushing yards (536) entering week six. Can a wobbly Seahawks front seven answer the call on Thursday night? Consider me unconvinced. Seattle will struggle (again) defensively and its uneven offense will fail to keep pace. A second consecutive short week won't do this team any wonders."

Scott Hanson, Seattle Times: 49ers 31, Seahawks 21

"Both teams are coming off bad losses, but this game might be more important for the 49ers (2-3) than the Seahawks (3-2). It's hard to see how Seahawks can stop the 49ers offense when it could not stop the Lions or the Giants."

Lorenzo Reyes, USA Today: 49ers 25, Seahawks 17

"There is some concern over San Francisco's recent issues finishing games, but the good news for the Niners is many of the issues cropped up because of self-inflicted errors. The 49ers are very talented and should be able to increase their discipline and focus. This could also serve as a wake-up call and might be a nice buy-low chance. And Seattle is too unreliable."

Tyler Dragon, USA Today: 49ers 25, Seahawks 20

"Are the 49ers in the midst of a Super Bowl hangover? They had a two-score lead at home in the second half against Arizona last week and still managed to lose. San Francisco is underachieving at the moment. Seattle at 3-2 is the only team in the NFC West with a winning record. But the Seahawks have lost five consecutive games versus San Francisco."

Jordan Mendoza, USA Today: 49ers 26, Seahawks 20

"Two teams needing to turn the page, expect the defenses to hold up early before each offense breaks through. Even if it's in Seattle, the 49ers have won two-straight at Lumen Field. Make it three-in-a-row to put a tie on top of the NFC West."

Bill Bender, Sporting News: 49ers 24, Seahawks 20

"The 49ers rank second in the NFL in yards per game (407.4), but they are 0-2 S/U on the road. San Francisco has struggled in the red zone on offense. Will a Seattle defense that has allowed 35.5 points per game in losses to the Lions and Giants the past two weeks be the cure? Seattle is 1-4 ATS this season."

Pete Prisco, CBS Sports: 49ers 30, Seahawks 20

"This looked like a big game three weeks ago in terms of league stature, but both teams have struggled lately. It is a big game as far as the division. The Seahawks have major issue on defense right now, which I think will show up. Look for Brock Purdy to have a good day as the 49ers get back on track."